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Literature summary extracted from

  • Campo, G.M.; Avenoso, A.; Campo, S.; DAscola, A.; Traina, P.; Calatroni, A.
    Effect of cytokines on hyaluronan synthase activity and response to oxidative stress by fibroblasts (2009), Br. J. Biomed. Sci., 66, 28-36.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.212 Homo sapiens O00219 isoform HAS3
-
2.4.1.212 Homo sapiens Q92819 isoform HAS2
-
2.4.1.212 Homo sapiens Q92839 isoform HAS1
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.212 DPK-SKDF-H cell
-
 Homo sapiens
-
2.4.1.212 DPK-SKDF-H cell skin dermal fibroblast cell Homo sapiens
-

Expression

EC Number Organism Comment Expression
2.4.1.212 Homo sapiens transforming grwoth factor 1beta significantly inhibits HAS3 expression and protein formation down
2.4.1.212 Homo sapiens both tumor necrosis factor TNFalpha and interferon INFgamma significantly induce HAS3 expression up
2.4.1.212 Homo sapiens both tumor necrosis factor TNFalpha and transforming growth factor 1beta significantly increase HAS1 expression and protein synthesis. Exposure to reactive oxygen species results in increased gene expression and protein formation of HAS1 up
2.4.1.212 Homo sapiens both tumor necrosis factor TNFalpha and transforming growth factor 1beta significantly increase HAS2 expression and protein synthesis. Exposure to reactive oxygen species results in increased gene expression and protein formation of HAS2 up